Molecular weight (DA)
45kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Specificity
SSR3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
function:Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.,PTM:Phosphorylated. Phosphorylation increases upon somatostatin binding.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Internalized into endoplasmic vesicles upon somatostatin-stimulation.,tissue specificity:Brain, pituitary and pancreas.,
Protein name
Somatostatin receptor type 3 (SS-3-R) (SS3-R) (SS3R) (SSR-28)
Fields
>>Neuroactive ligand-receptor interaction;>>Growth hormone synthesis, secretion and action
Human protein sequence Database
P32745
Mouse protein sequence database
P30935
Rat protein sequence database
P30936
Cellular localization
Cell membrane ; Multi-pass membrane protein . Internalized into endoplasmic vesicles upon somatostatin-stimulation. .
Tissue expression
Brain, pituitary and pancreas.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车