Molecular weight (DA)
14kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 370-450
Specificity
F19A5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
family with sequence similarity 19 member A5, C-C motif chemokine like(FAM19A5) Homo sapiens This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells. [provided by RefSeq, Sep 2013],
Function
similarity:Belongs to the FAM19/TAFA family.,tissue specificity:Isoform 2 is brain-specific.,
Gene Name
FAM19A5 TAFA5 UNQ5208/PRO34524
Protein name
Protein FAM19A5 (Chemokine-like protein TAFA-5)
Human protein sequence Database
Q7Z5A7
Mouse protein sequence database
Q91WE9
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Expressed in the subcutaneous and perirenal adipose tissue (at protein level) (PubMed:29453251). Highly expressed in adipose tissue with moderate expression in the brain and ovary (PubMed:29453251). Isoform 2: Brain-specific (PubMed:15028294).
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