Molecular weight (DA)
49kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RGMA Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
Function
function:Repulsive guidance molecules (Rgm) are involved in the guidance of growth cones of the developing neurons.,similarity:Belongs to the repulsive guidance molecule (RGM) family.,
Protein name
Repulsive guidance molecule A (RGM domain family member A)
Fields
>>TGF-beta signaling pathway;>>Axon guidance
Human protein sequence Database
Q96B86
Mouse protein sequence database
Q6PCX7
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor .
Tissue expression
Retina,Teratocarcinoma,Testis,Uterus,
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