Molecular weight (DA)
36kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
FACE2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq, Jul 2008],
Function
function:Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1.,similarity:Belongs to the peptidase U48 family.,tissue specificity:Ubiquitous.,
Gene Name
RCE1 FACE2 RCE1A RCE1B
Protein name
CAAX prenyl protease 2 (EC 3.4.22.-) (Farnesylated proteins-converting enzyme 2) (FACE-2) (Prenyl protein-specific endoprotease 2) (RCE1 homolog) (hRCE1)
Fields
>>Terpenoid backbone biosynthesis
Human protein sequence Database
Q9Y256
Mouse protein sequence database
P57791
Rat protein sequence database
B0BMW8
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Tissue expression
Ubiquitous.
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