Molecular weight (DA)
46kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
TICN2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
Function
function:May participate in diverse steps of neurogenesis. Binds calcium.,PTM:Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.,similarity:Contains 1 Kazal-like domain.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Highly expressed in brain. Also found in lung and testis.,
Gene Name
SPOCK2 KIAA0275 TICN2 UNQ269/PRO306
Protein name
Testican-2 (SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 2)
Human protein sequence Database
Q92563
Mouse protein sequence database
Q9ER58
Rat protein sequence database
Cellular localization
Secreted, extracellular space, extracellular matrix .
Tissue expression
Highly expressed in brain. Also found in lung and testis.
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