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AIRP Polyclonal Antibody

Polyclonal antibody

Specification

BYab-13866

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Host
Reactiveness
Use
Molecular weight (DA)
69kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NT5C1B. AA range:171-220
Specificity
AIRP Polyclonal Antibody detects endogenous levels of AIRP protein.
Source
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Background
Cytosolic 5-prime nucleotidases, such as NT5C1B, catalyze production of adenosine, which regulates diverse physiologic processes (Sala-Newby and Newby, 2001 [PubMed 11690631]).[supplied by OMIM, Mar 2008],
Function
catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.,function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.,similarity:Belongs to the 5'-nucleotidase type 3 family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,tissue specificity:Expressed in brain, kidney, pancreas and placenta.,tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.,
Gene Name
NT5C1B
Protein name
Cytosolic 5'-nucleotidase 1B
Abbreviation
AIRP
Other name
NT5C1B; AIRP; FKSG85; Cytosolic 5'-nucleotidase 1B; cN1B; Autoimmune infertility-related protein; Cytosolic 5'-nucleotidase IB; cN-IB
Fields
>>Purine metabolism;>>Pyrimidine metabolism;>>Nicotinate and nicotinamide metabolism;>>Metabolic pathways;>>Nucleotide metabolism
Human gene ID
93034
Human protein sequence Database
Q96P26
Mouse gene ID
Mouse protein sequence database
Q91YE9
Rat gene ID
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung.
Storage
-20°C/1 year

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AIRP Polyclonal Antibody

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