Molecular weight (DA)
80kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SKI Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
SKI proto-oncogene(SKI) Homo sapiens This gene encodes the nuclear protooncogene protein homolog of avian sarcoma viral (v-ski) oncogene. It functions as a repressor of TGF-beta signaling, and may play a role in neural tube development and muscle differentiation. [provided by RefSeq, Oct 2009],
Function
function:May play a role in terminal differentiation of skeletal muscle cells but not in the determination of cells to the myogenic lineage.,similarity:Belongs to the SKI family.,subunit:Interacts with SMAD2, SMAD3 and SMAD4. Interacts with HIPK2. Part of a complex with HIPK2 and SMAD1/2/3.,
Protein name
Ski oncogene (Proto-oncogene c-Ski)
Human protein sequence Database
P12755
Mouse protein sequence database
Q60698
Rat protein sequence database
Cellular localization
Nucleus.
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