Molecular weight (DA)
54kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CDK16 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009],
Function
similarity:Belongs to the protein kinase superfamily.,
Protein name
Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
Human protein sequence Database
Q00536
Mouse protein sequence database
Q04735
Rat protein sequence database
Q63686
Cellular localization
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, synaptosome . Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY.
Tissue expression
Detected in pancreas islets (at protein level). Detected in brain and pancreas.
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