Molecular weight (DA)
174kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
NRK Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Nik related kinase(NRK) Homo sapiens The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May phosphorylate cofilin-1 and induce actin polymerization through this process, during the late stages of embryogenesis. Involved in the TNF-alpha-induced signaling pathway.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,
Protein name
Nik-related protein kinase (EC 2.7.11.1)
Human protein sequence Database
Q7Z2Y5
Mouse protein sequence database
Q9R0G8
Rat protein sequence database
Cellular localization
cytoplasm,integral component of membrane,
Tissue expression
Fetal kidney,Ovary,Placenta,
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