Molecular weight (DA)
30kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Specificity
LBX1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq, Jul 2008],
Function
function:Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with LBXCOR1 which acts as a transcriptional corepressor.,
Protein name
Transcription factor LBX1 (Ladybird homeobox protein homolog 1)
Human protein sequence Database
P52954
Mouse protein sequence database
P52955
Rat protein sequence database
Q1XID0
Cellular localization
Nucleus .
Tissue expression
Bone marrow,
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