Molecular weight (DA)
46kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SYT15 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
synaptotagmin 15(SYT15) Homo sapiens This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
domain:Neither C2 domains mediates Ca(2+)-dependent or -independent phospholipid binding.,function:May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer.,
Protein name
Synaptotagmin-15 (Chr10Syt) (Synaptotagmin XV) (SytXV)
Human protein sequence Database
Q9BQS2
Mouse protein sequence database
Q8C6N3
Rat protein sequence database
P59926
Cellular localization
[Isoform 1]: Cell membrane ; Single-pass type III membrane protein .; [Isoform 2]: Cell membrane ; Single-pass type III membrane protein .; [Isoform 4]: Cell membrane ; Single-pass type III membrane protein .
Tissue expression
Brain,Cerebellum,Donated clones,Heart,Thalamus,
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