Molecular weight (DA)
43kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
VAT1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
vesicle amine transport 1(VAT1) Homo sapiens Synaptic vesicles are responsible for regulating the storage and release of neurotransmitters in the nerve terminal. The protein encoded by this gene is an abundant integral membrane protein of cholinergic synaptic vesicles and is thought to be involved in vesicular transport. It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,
Protein name
Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-)
Human protein sequence Database
Q99536
Mouse protein sequence database
Q62465
Rat protein sequence database
Q3MIE4
Cellular localization
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. The majority is localized in the cytoplasm and a small amount is associated with mitochondria. .
Tissue expression
Expressed in brain. Also expressed in glioblastoma cells.
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