Molecular weight (DA)
22kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SIKE1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008],
Protein name
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)
Fields
>>RIG-I-like receptor signaling pathway
Human protein sequence Database
Q9BRV8
Mouse protein sequence database
Q9CPR7
Rat protein sequence database
Q5FWT9
Cellular localization
Cytoplasm .
Tissue expression
Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and leukocytes. Present in all cell lines tested (at protein level).