Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 60-140
Specificity
PAIRB Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.,
Function
function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.,
Gene Name
SERBP1 PAIRBP1 CGI-55
Protein name
Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1)
Human protein sequence Database
Q8NC51
Mouse protein sequence database
Q9CY58
Rat protein sequence database
Q6AXS5
Cellular localization
Cytoplasm . Nucleus . Cytoplasm, perinuclear region .
Tissue expression
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain.
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