Molecular weight (DA)
15kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Specificity
STP2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.,similarity:Belongs to the nuclear transition protein 2 family.,tissue specificity:Testis.,
Function
function:In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins.,similarity:Belongs to the nuclear transition protein 2 family.,tissue specificity:Testis.,
Protein name
Nuclear transition protein 2 (TP-2) (TP2)
Human protein sequence Database
Q05952
Mouse protein sequence database
P11378
Rat protein sequence database
P11101
Cellular localization
Nucleus . Chromosome . Loaded onto the nucleosomes of condensing spermatids (By similarity). Nuclear import is ATP-dependent and nucleolar localization requires the protein to be phosphorylated (By similarity). .
Tissue expression
Expressed by spermatids (at protein level).
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