Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Specificity
LHX5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008],
Function
function:Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum.,
Protein name
LIM/homeobox protein Lhx5 (LIM homeobox protein 5)
Fields
>>Signaling pathways regulating pluripotency of stem cells
Human protein sequence Database
Q9H2C1
Mouse protein sequence database
P61375
Rat protein sequence database
P61376
Cellular localization
Nucleus .
Tissue expression
Expressed in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum.
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