Molecular weight (DA)
45kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CBPB1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Three different procarboxypeptidases A and two different procarboxypeptidases B have been isolated. The B1 and B2 forms differ from each other mainly in isoelectric point. Carboxypeptidase B1 is a highly tissue-specific protein and is a useful serum marker for acute pancreatitis and dysfunction of pancreatic transplants. It is not elevated in pancreatic carcinoma. [provided by RefSeq, Jul 2008],
Function
catalytic activity:Preferential release of a C-terminal lysine or arginine amino acid.,cofactor:Binds 1 zinc ion per subunit.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Pancreas.,
Protein name
Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP)
Fields
>>Pancreatic secretion;>>Protein digestion and absorption
Human protein sequence Database
P15086
Mouse protein sequence database
Rat protein sequence database
P19223
Cellular localization
Secreted . Zymogen granule lumen .
Tissue expression
Pancreas.
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