Molecular weight (DA)
30kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CABP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Function
disease:Defects in CABP4 are the cause of congenital stationary night blindness type 2B (CSNB2B) [MIM:610427]. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.,function:May play a role in normal synaptic function, probably through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals. Modulator of CACNA1F, shifting the activation range to more hyperpolarized voltages.,similarity:Contains 4 EF-hand domains.,subcellular location:Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.,subunit:Interacts with CACNA1F.,
Protein name
Calcium-binding protein 4 (CaBP4)
Human protein sequence Database
P57796
Mouse protein sequence database
Q8VHC5
Rat protein sequence database
Cellular localization
Cytoplasm . Cell junction, synapse, presynapse . Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors. .
Tissue expression
Expressed in retina and in the inner hair cells (IHC) of the cochlea.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车