Molecular weight (DA)
35kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 200-280
Specificity
B2L14 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009],
Function
function:May play a role in apoptosis.,similarity:Belongs to the Bcl-2 family.,subcellular location:Diffusely distributed throughout the cytosol.,subcellular location:Predominantly localized to cytosolic organelles.,tissue specificity:Isoform 1 is widely expressed and isoform 2 is testis-specific.,
Protein name
Apoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)
Human protein sequence Database
Q9BZR8
Mouse protein sequence database
Q9CPT0
Rat protein sequence database
Q6AYK4
Cellular localization
Cytoplasm .; [Isoform 1]: Cytoplasm, cytosol. Diffusely distributed throughout the cytosol.; [Isoform 2]: Endomembrane system. Predominantly localized to cytosolic organelles.
Tissue expression
Isoform 1 is widely expressed. Isoform 2 is testis-specific.