Molecular weight (DA)
37kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Specificity
PDCD2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010],
Function
function:May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.,similarity:Contains 1 MYND-type zinc finger.,tissue specificity:Ubiquitous.,
Gene Name
PDCD2 RP8 ZMYND7
Protein name
Programmed cell death protein 2 (Zinc finger MYND domain-containing protein 7) (Zinc finger protein Rp-8)
Human protein sequence Database
Q16342
Mouse protein sequence database
P46718
Rat protein sequence database
P47816
Cellular localization
Nucleus .
Tissue expression
Ubiquitous.
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