Molecular weight (DA)
20kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Specificity
IFN21 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the alpha interferon gene cluster on the short arm of chromosome 9. Interferons are cytokines produced in response to viral infection that mediate the immune response and interfere with viral replication. The encoded protein is a type I interferon and may play a specific role in the antiviral response to rubella virus. [provided by RefSeq, Sep 2011],
Function
function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,similarity:Belongs to the alpha/beta interferon family.,
Protein name
Interferon alpha-21 (IFN-alpha-21) (Interferon alpha-F) (LeIF F)
Fields
>>Cytokine-cytokine receptor interaction;>>PI3K-Akt signaling pathway;>>Necroptosis;>>Toll-like receptor signaling pathway;>>NOD-like receptor signaling pathway;>>RIG-I-like receptor signaling pathway;>>Cytosolic DNA-sensing pathway;>>JAK-STAT signaling pathway;>>Natural killer cell mediated cytotoxicity;>>Alcoholic liver disease;>>Tuberculosis;>>Hepatitis C;>>Hepatitis B;>>Measles;>>Human cytomegalovirus infection;>>Influenza A;>>Human papillomavirus infection;>>Kaposi sarcoma-associated herpesvirus infection;>>Herpes simplex virus 1 infection;>>Epstein-Barr virus infection;>>Human immunodeficiency virus 1 infection;>>Coronavirus disease - COVID-19;>>Pathways in cancer;>>Autoimmune thyroid disease;>>Lipid and atherosclerosis
Human protein sequence Database
P01568
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Lymphoblast,
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