Molecular weight (DA)
23kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Specificity
RRAS Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015],
Function
function:Regulates the organization of the actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).,subunit:Interacts with PLCE1.,
Protein name
Ras-related protein R-Ras (p23)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>cAMP signaling pathway;>>Phospholipase D signaling pathway;>>Mitophagy - animal;>>Autophagy - animal;>>Cellular senescence;>>Axon guidance;>>Apelin signaling pathway;>>C-type lectin receptor signaling pathway;>>Regulation of actin cytoskeleton;>>Salmonella infection;>>Proteoglycans in cancer
Human protein sequence Database
P10301
Mouse protein sequence database
P10833
Rat protein sequence database
D3Z8L7
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).
Tissue expression
Adipocyte,Brain,Uterus,