Immunogen
Synthetic peptide from human protein at AA range: 90-131
Specificity
The antibody detects endogenous MIA
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.,PTM:May possess two intramolecular disulfide bonds.,similarity:Belongs to the MIA/OTOR family.,similarity:Contains 1 SH3 domain.,tissue specificity:All malignant melanoma cell lines tested and infrequently in glioma cell lines.,
Function
function:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.,PTM:May possess two intramolecular disulfide bonds.,similarity:Belongs to the MIA/OTOR family.,similarity:Contains 1 SH3 domain.,tissue specificity:All malignant melanoma cell lines tested and infrequently in glioma cell lines.,
Protein name
Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein)
Other name
Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein)
Human protein sequence Database
Q16674
Mouse protein sequence database
Q61865
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
All malignant melanoma cell lines tested and infrequently in glioma cell lines.
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