Molecular weight (DA)
46kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PAI-2. AA range:258-307
Specificity
PAI-2 Polyclonal Antibody detects endogenous levels of PAI-2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.,PTM:The signal sequence is not cleaved.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,
Function
function:Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.,PTM:The signal sequence is not cleaved.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,
Protein name
Plasminogen activator inhibitor 2
Other name
SERPINB2; PAI2; PLANH2; Plasminogen activator inhibitor 2; PAI-2; Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor
Fields
>>Complement and coagulation cascades
Human protein sequence Database
P05120
Mouse protein sequence database
P12388
Rat protein sequence database
Cellular localization
Cytoplasm. Secreted, extracellular space.
Tissue expression
Brain,Monocyte,Placenta,
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