Molecular weight (DA)
67kD
Immunogen
The antiserum was produced against synthesized peptide derived from human EPS8L3. AA range:401-450
Specificity
Eps8L3 Polyclonal Antibody detects endogenous levels of Eps8L3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the EPS8 family.,similarity:Contains 1 SH3 domain.,subunit:Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2.,
Protein name
Epidermal growth factor receptor kinase substrate 8-like protein 3
Other name
EPS8L3; EPS8R3; Epidermal growth factor receptor kinase substrate 8-like protein 3; EPS8-like protein 3; Epidermal growth factor receptor pathway substrate 8-related protein 3; EPS8-related protein 3
Human protein sequence Database
Q8TE67
Mouse protein sequence database
Q91WL0
Rat protein sequence database
Cellular localization
Cytoplasm .
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