Immunogen
The antiserum was produced against synthesized peptide derived from human EIF1AY. AA range:21-70
Specificity
eIF1AY Polyclonal Antibody detects endogenous levels of eIF1AY protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
function:Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.,similarity:Belongs to the eIF-1A family.,similarity:Contains 1 S1-like domain.,tissue specificity:Ubiquitous.,
Protein name
Eukaryotic translation initiation factor 1A Y-chromosomal
Other name
EIF1AY; Eukaryotic translation initiation factor 1A; Y-chromosomal; eIF-1A Y isoform; Eukaryotic translation initiation factor 4C; eIF-4C
Human protein sequence Database
O14602
Mouse protein sequence database
Rat protein sequence database
Tissue expression
Ubiquitous.
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