Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CNPase. AA range:59-108
Specificity
CNPase Polyclonal Antibody detects endogenous levels of CNPase protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate.,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,subcellular location:Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
Function
catalytic activity:Nucleoside 2',3'-cyclic phosphate + H(2)O = nucleoside 2'-phosphate.,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,subcellular location:Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
Protein name
2',3'-cyclic-nucleotide 3'-phosphodiesterase
Other name
CNP; 2'; 3'-cyclic-nucleotide 3'-phosphodiesterase; CNP; CNPase
Human protein sequence Database
P09543
Mouse protein sequence database
P16330
Rat protein sequence database
P13233
Cellular localization
Membrane ; Lipid-anchor . Melanosome . Firmly bound to membrane structures of brain white matter. .
Tissue expression
Brain,Skin,
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