Molecular weight (DA)
65kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARMCX2. AA range:321-370
Specificity
ARMCX2 Polyclonal Antibody detects endogenous levels of ARMCX2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
armadillo repeat containing, X-linked 2(ARMCX2) Homo sapiens This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013],
Function
similarity:Contains 3 ARM repeats.,tissue specificity:Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not expressed in pancreas and ovarian carcinomas.,
Protein name
Armadillo repeat-containing X-linked protein 2
Other name
ARMCX2; ALEX2; KIAA0512; Armadillo repeat-containing X-linked protein 2; ARM protein lost in epithelial cancers on chromosome X 2; Protein ALEX2
Human protein sequence Database
Q7L311
Mouse protein sequence database
Q6A058
Rat protein sequence database
Cellular localization
Mitochondrion . Mitochondrion outer membrane ; Single-pass membrane protein .
Tissue expression
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not expressed in pancreas and ovarian carcinomas.
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