Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NDUFA9. AA range:87-136
Specificity
NDUFA9 Polyclonal Antibody detects endogenous levels of NDUFA9 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex I), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane. A pseudogene has been identified on chromosome 12. [provided by RefSeq, May 2010],
Function
cofactor:Binds 1 FAD per subunit.,function:Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.,similarity:Belongs to the complex I NDUFA9 subunit family.,subunit:Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.,
Protein name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 mitochondrial
Other name
NDUFA9; NDUFS2L; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9; mitochondrial; Complex I-39kD; CI-39kD; NADH-ubiquinone oxidoreductase 39 kDa subunit
Fields
>>Oxidative phosphorylation;>>Metabolic pathways;>>Thermogenesis;>>Retrograde endocannabinoid signaling;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
Human protein sequence Database
Q16795
Mouse protein sequence database
Q9DC69
Rat protein sequence database
Q5BK63
Cellular localization
Mitochondrion matrix .
Tissue expression
Blood,Colon,Liver,Muscle,Placenta,Skeletal muscle,