Immunogen
The antiserum was produced against synthesized peptide derived from human NBPF4. AA range:48-97
Specificity
NBPF4 Polyclonal Antibody detects endogenous levels of NBPF4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
neuroblastoma breakpoint family member 4(NBPF4) Homo sapiens This gene is a member of the neuroblastoma breakpoint family (NBPF) which consists of dozens of recently duplicated genes primarily located in segmental duplications on human chromosome 1. This gene family has experienced its greatest expansion within the human lineage and has expanded, to a lesser extent, among primates in general. Members of this gene family are characterized by tandemly repeated copies of DUF1220 protein domains. Gene copy number variations in the human chromosomal region 1q21.1, where most DUF1220 domains are located, have been implicated in a number of developmental and neurogenetic diseases such as microcephaly, macrocephaly, autism, schizophrenia, mental retardation, congenital heart disease, neuroblastoma, and congenital kidney and urinary tract anomalies. Altered expression of some gene family members is associated with several types of cancer. This gene fam
Function
miscellaneous:Encoded by one of the numerous copies of NBPF genes clustered in the p36, p12 and q21 region of the chromosome 1.,similarity:Belongs to the NBPF family.,similarity:Contains 3 NBPF domains.,tissue specificity:Expressed in testis.,
Protein name
Neuroblastoma breakpoint family member 4
Other name
NBPF4; Neuroblastoma breakpoint family member 4
Human protein sequence Database
Q96M43
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Expressed in testis.
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