Molecular weight (DA)
50kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AGXT2L2. AA range:341-390
Specificity
AGXT2L2 Polyclonal Antibody detects endogenous levels of AGXT2L2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
5-phosphohydroxy-L-lysine phospho-lyase(PHYKPL) Homo sapiens This is a nuclear gene encoding a mitochondrial enzyme that catalyzes the conversion of 5-phosphonooxy-L-lysine to ammonia, inorganic phosphate, and 2-aminoadipate semialdehyde. Mutations in this gene may cause phosphohydroxylysinuria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Function
cofactor:Pyridoxal phosphate .,similarity:Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homotetramer.,
Protein name
5-phosphohydroxy-L-lysine phospho-lyase
Other name
AGXT2L2; PP9286; 5-phosphohydroxy-L-lysine phospho-lyase; Alanine--glyoxylate aminotransferase 2-like 2
Fields
>>Lysine degradation;>>Metabolic pathways
Human protein sequence Database
Q8IUZ5
Mouse protein sequence database
Q8R1K4
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Brain,Muscle,Pancreas,Stomach,
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