Molecular weight (DA)
87kD
Immunogen
Synthesized peptide derived from ADAM32 . at AA range: 460-540
Specificity
ADAM32 Polyclonal Antibody detects endogenous levels of ADAM32 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ADAM metallopeptidase domain 32(ADAM32) Homo sapiens This gene encodes a member of the disintegrin family of membrane-anchored proteins that play a role in diverse biological processes such as brain development, fertilization, tumor development and inflammation. This gene is predominantly expressed in the testis. The encoded protein undergoes proteolytic processing to generate a mature polypeptide comprised of an metalloprotease, disintegrin and epidermal growth factor-like domains. This gene is located in a cluster of other disintegrin and metallopeptidase family genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015],
Function
function:May play a role in sperm development and fertilization This is a non-catalytic metalloprotease-like protein.,similarity:Contains 1 disintegrin domain.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 peptidase M12B domain.,tissue specificity:Testis specific.,
Protein name
Disintegrin and metalloproteinase domain-containing protein 32
Other name
ADAM32; Disintegrin and metalloproteinase domain-containing protein 32; ADAM 32
Human protein sequence Database
Q8TC27
Mouse protein sequence database
Q8K410
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Testis specific.
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