Immunogen
The antiserum was produced against synthesized peptide derived from human RFX2. AA range:661-710
Specificity
RFX2 Polyclonal Antibody detects endogenous levels of RFX2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the RFX family.,
Protein name
DNA-binding protein RFX2
Other name
RFX2; DNA-binding protein RFX2; Regulatory factor X 2
Human protein sequence Database
P48378
Mouse protein sequence database
P48379
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Mainly expressed in the nucleus and at lower level in cytoplasm. .
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