Molecular weight (DA)
110kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512
Specificity
NFRκB Polyclonal Antibody detects endogenous levels of NFRκB protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
Function
function:Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit:Component of the chromatin-remodeling INO80 complex, at least composed of ACTL6A, ACTR5, ACTR8, RVBL1, RVBL2, INO80, INO80B, INO80C, INO80D and INO80E.,tissue specificity:Expressed in thymus, brain, testes, spleen and liver.,
Protein name
Nuclear factor related to kappa-B-binding protein
Other name
NFRKB; INO80G; Nuclear factor related to kappa-B-binding protein; DNA-binding protein R kappa-B; INO80 complex subunit G
Human protein sequence Database
Q6P4R8
Mouse protein sequence database
Q6PIJ4
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Expressed in thymus, brain, testes, spleen and liver.
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