Molecular weight (DA)
29kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 90-170
Specificity
IBP5 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Osteosarcoma, and at lower levels in liver, kidney and brain.,
Function
function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,tissue specificity:Osteosarcoma, and at lower levels in liver, kidney and brain.,
Protein name
Insulin-like growth factor-binding protein 5 (IBP-5) (IGF-binding protein 5) (IGFBP-5)
Human protein sequence Database
P24593
Mouse protein sequence database
Q07079
Rat protein sequence database
P24594
Cellular localization
Secreted.
Tissue expression
Osteosarcoma, and at lower levels in liver, kidney and brain.
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