Molecular weight (DA)
50kD
Immunogen
The antiserum was produced against synthesized peptide derived from human FOXN4. AA range:411-460
Specificity
FoxN4 Polyclonal Antibody detects endogenous levels of FoxN4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Members of the winged-helix/forkhead family of transcription factors, such as FOXN4, are characterized by a 110-amino acid DNA-binding domain that can fold into a variant of the helix-turn-helix motif consisting of 3 alpha helices flanked by 2 large loops or wings. These transcription factors are involved in a variety of biologic processes as key regulators in development and metabolism (Li et al., 2004 [PubMed 15363391]).[supplied by OMIM, Mar 2008],
Function
similarity:Contains 1 fork-head DNA-binding domain.,
Protein name
Forkhead box protein N4
Other name
FOXN4; Forkhead box protein N4
Human protein sequence Database
Q96NZ1
Mouse protein sequence database
Q8K3Q3
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Brain,Clones donated by RIKEN,
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