Molecular weight (DA)
15kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human RBP2. AA range:71-120
Specificity
CRBP II Polyclonal Antibody detects endogenous levels of CRBP II protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
retinol binding protein 2(RBP2) Homo sapiens This gene encodes an abundant protein present in the small intestinal epithelium. It is thought to participate in the uptake and/or intracellular metabolism of vitamin A. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. This protein may also modulate the supply of retinoic acid to the nuclei of endometrial cells during the menstrual cycle. [provided by RefSeq, Aug 2015],
Function
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Intracellular transport of retinol.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Higher expression in adult small intestine and to a much lesser extent in fetal kidney.,
Protein name
Retinol-binding protein 2
Other name
RBP2; CRBP2; Retinol-binding protein 2; Cellular retinol-binding protein II; CRBP-II
Fields
>>Vitamin digestion and absorption
Human protein sequence Database
P50120
Mouse protein sequence database
Q08652
Rat protein sequence database
P06768
Cellular localization
Cytoplasm.
Tissue expression
Higher expression in adult small intestine and to a much lesser extent in fetal kidney.
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