Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human EEF1G. AA range:101-150
Specificity
EF-1 γ Polyclonal Antibody detects endogenous levels of EF-1 γ protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
eukaryotic translation elongation factor 1 gamma(EEF1G) Homo sapiens This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008],
Function
function:Probably plays a role in anchoring the complex to other cellular components.,similarity:Contains 1 EF-1-gamma C-terminal domain.,similarity:Contains 1 GST C-terminal domain.,similarity:Contains 1 GST N-terminal domain.,subunit:EF-1 is composed of four subunits: alpha, beta, delta, and gamma.,tissue specificity:Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.,
Protein name
Elongation factor 1-gamma
Other name
EEF1G; EF1G; Elongation factor 1-gamma; EF-1-gamma; eEF-1B gamma
Human protein sequence Database
P26641
Mouse protein sequence database
Q9D8N0
Rat protein sequence database
Q68FR6
Cellular localization
nucleus,cytoplasm,endoplasmic reticulum,cytosol,cell-cell adherens junction,membrane,extracellular exosome,
Tissue expression
Highly expressed in pancreatic tumor tissue and to a lesser extent in normal kidney, intestine, pancreas, stomach, lung, brain, spleen and liver.
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