Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ZDHHC7. AA range:259-308
Specificity
DHHC-7 Polyclonal Antibody detects endogenous levels of DHHC-7 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and regulate their synaptic clustering and/or cell surface stability.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,
Function
catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:Palmitoyltransferase with broad specificity. Palmitoylates SNAP25 and DLG4/PSD95. May palmitoylate GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3) and regulate their synaptic clustering and/or cell surface stability.,similarity:Belongs to the DHHC palmitoyltransferase family.,similarity:Contains 1 DHHC-type zinc finger.,
Protein name
Palmitoyltransferase ZDHHC7
Other name
ZDHHC7; ZNF370; Palmitoyltransferase ZDHHC7; Zinc finger DHHC domain-containing protein 7; DHHC-7; Zinc finger protein 370
Human protein sequence Database
Q9NXF8
Mouse protein sequence database
Q91WU6
Rat protein sequence database
Cellular localization
Golgi apparatus membrane ; Multi-pass membrane protein .
Tissue expression
Duodenal mucosa,Hepatoma,Skin,Teratocarcinoma,
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