Immunogen
Recombinant Protein of TLR13
Specificity
The antibody detects endogenous TLR13 protein.
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Dilution rate
IHC: 1:200-500. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The TLRs form a family of ligand-binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Protein name
Toll-like receptor 13
Human protein sequence Database
Mouse protein sequence database
Rat protein sequence database