Immunogen
The antiserum was produced against synthesized peptide derived from human TRAPPC6A. AA range:31-80
Specificity
TRAPPC6A Polyclonal Antibody detects endogenous levels of TRAPPC6A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein may be involved in melanosome biogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],
Function
function:May play a role in vesicular transport during the biogenesis of melanosomes.,similarity:Belongs to the TRAPP small subunits family. BET3 subfamily.,subunit:Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3.,
Protein name
Trafficking protein particle complex subunit 6A
Other name
TRAPPC6A; HSPC289; Trafficking protein particle complex subunit 6A; TRAPP complex subunit 6A
Human protein sequence Database
O75865
Mouse protein sequence database
Q78XR0
Rat protein sequence database
Cellular localization
Golgi apparatus, cis-Golgi network . Endoplasmic reticulum .
Tissue expression
Lung,Umbilical cord blood,
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