Molecular weight (DA)
72kD
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human LY9. AA range:261-310
Specificity
CD229 Polyclonal Antibody detects endogenous levels of CD229 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008],
Function
alternative products:Experimental confirmation may be lacking for some isoforms,function:May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,
Protein name
T-lymphocyte surface antigen Ly-9
Other name
LY9; CDABP0070; T-lymphocyte surface antigen Ly-9; Cell surface molecule Ly-9; Lymphocyte antigen 9; CD229
Human protein sequence Database
Q9HBG7
Mouse protein sequence database
Q01965
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein. Cell membrane .
Tissue expression
Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.
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