Molecular weight (DA)
70kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC6A6. AA range:561-610
Specificity
TAUT Polyclonal Antibody detects endogenous levels of TAUT protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a multi-pass membrane protein that is a member of a family of sodium and chloride-ion dependent transporters. The encoded protein transports taurine and beta-alanine. There is a pseudogene for this gene on chromosome 21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],
Function
function:Required for the uptake of taurine.,PTM:Down-regulated upon Ser-322 phosphorylation.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,
Protein name
Sodium- and chloride-dependent taurine transporter
Other name
SLC6A6; Sodium- and chloride-dependent taurine transporter; Solute carrier family 6 member 6
Human protein sequence Database
P31641
Mouse protein sequence database
O35316
Rat protein sequence database
P31643
Cellular localization
Cell membrane ; Multi-pass membrane protein .
Tissue expression
Expressed abundantly in placenta and skeletal muscle, at intermediate levels in heart, brain, lung, kidney and pancreas and at low levels in liver.
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