Molecular weight (DA)
32kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SCAMP1. AA range:273-322
Specificity
SCAMP1 Polyclonal Antibody detects endogenous levels of SCAMP1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
Function
function:Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.,similarity:Belongs to the SCAMP family.,subunit:Interacts with AP1GBP1 and ITSN1 (By similarity). Interacts with SLC9A7.,tissue specificity:Widely expressed, with highest expression in brain.,
Protein name
Secretory carrier-associated membrane protein 1
Other name
SCAMP1; SCAMP; Secretory carrier-associated membrane protein 1; Secretory carrier membrane protein 1
Human protein sequence Database
O15126
Mouse protein sequence database
Q8K021
Rat protein sequence database
P56603
Cellular localization
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein .
Tissue expression
Widely expressed, with highest expression in brain.
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