Molecular weight (DA)
实测条带：
16kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
AIF1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500 - 1:2000. ELISA: 1:5000. IF 1:100-300 Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
Function
function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,
Protein name
Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
Human protein sequence Database
P55008
Mouse protein sequence database
O70200
Rat protein sequence database
P55009
Cellular localization
Cytoplasm, cytoskeleton . Cell projection, ruffle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, phagocytic cup . Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis. .
Tissue expression
Detected in T-lymphocytes and peripheral blood mononuclear cells.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
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