Molecular weight (DA)
50kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MUC13. AA range:421-470
Specificity
Mucin 13 Polyclonal Antibody detects endogenous levels of Mucin 13 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Epithelial mucins, such as MUC13, are a family of secreted and cell surface glycoproteins expressed by ductal and glandular epithelial tissues (Williams et al., 2001 [PubMed 11278439]).[supplied by OMIM, Jul 2008],
Function
function:Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling.,PTM:Cleaved into two subunits, alpha and beta, probably between the first EGF domain and the SEA domain. Beta subunit contains the cytoplasmic tail and alpha subunit the extracellular tail. The homo-oligomerization into dimers is dependent on intrachain disulfide bonds.,PTM:Highly N-glycosylated.,similarity:Contains 1 SEA domain.,similarity:Contains 3 EGF-like domains.,subcellular location:Also exists as a soluble form.,subunit:Homodimer of beta subunits.,tissue specificity:Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.,
Other name
MUC13; DRCC1; RECC; Mucin-13; MUC-13; Down-regulated in colon cancer 1
Human protein sequence Database
Q9H3R2
Mouse protein sequence database
P19467
Rat protein sequence database
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Apical cell membrane . Secreted . Also exists as a soluble form.
Tissue expression
Highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车