Molecular weight (DA)
88kD
Immunogen
The antiserum was produced against synthesized peptide derived from human Integrin beta5. AA range:721-770
Specificity
Integrin β5 Polyclonal Antibody detects endogenous levels of Integrin β5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,
Function
function:Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 PSI domain.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-5 associates with alpha-V.,
Protein name
Integrin beta-5
Other name
ITGB5; Integrin beta-5
Fields
>>Phagosome;>>PI3K-Akt signaling pathway;>>Focal adhesion;>>ECM-receptor interaction;>>Regulation of actin cytoskeleton;>>Human papillomavirus infection;>>Proteoglycans in cancer;>>Hypertrophic cardiomyopathy;>>Arrhythmogenic right ventricular cardiomyopathy;>>Dilated cardiomyopathy
Human protein sequence Database
P18084
Mouse protein sequence database
O70309
Rat protein sequence database
Cellular localization
Membrane; Single-pass type I membrane protein.
Tissue expression
Brain,Kidney,Thymic epithelium,
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