Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen XXIII alpha1. AA range:461-510
Specificity
COL23A1 Polyclonal Antibody detects endogenous levels of COL23A1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
COL23A1 is a member of the transmembrane collagens, a subfamily of the nonfibrillar collagens that contain a single pass hydrophobic transmembrane domain (Banyard et al., 2003 [PubMed 12644459]).[supplied by OMIM, Mar 2008],
Function
PTM:Undergoes proteolytic cleavage by furin protease to yield a 60 kDa soluble form that forms an homotrimer and exhibits a low affinity interaction with heparin.,similarity:Contains 5 collagen-like domains.,subunit:Homotrimer.,
Protein name
Collagen alpha-1(XXIII) chain
Other name
COL23A1; Collagen alpha-1(XXIII) chain
Fields
>>Protein digestion and absorption
Human protein sequence Database
Q86Y22
Mouse protein sequence database
Q8K4G2
Rat protein sequence database
Q810Y4
Cellular localization
Cell membrane ; Single-pass type II membrane protein ; Extracellular side .
Tissue expression
Brain,Placenta,Testis,
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