Immunogen
The antiserum was produced against synthesized peptide derived from human CDON. AA range:511-560
Specificity
CDO Polyclonal Antibody detects endogenous levels of CDO protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a cell surface receptor that is a member of the immunoglobulin superfamily. The encoded protein contains three fibronectin type III domains and five immunoglobulin-like C2-type domains. This protein is a member of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells and positively regulates myogenesis. [provided by RefSeq, Aug 2011],
Function
function:Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells.,PTM:N-glycosylated.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3.,
Protein name
Cell adhesion molecule-related/down-regulated by oncogenes
Other name
CDON; CDO; Cell adhesion molecule-related/down-regulated by oncogenes
Fields
>>Hedgehog signaling pathway
Human protein sequence Database
Q4KMG0
Mouse protein sequence database
Q32MD9
Rat protein sequence database
Cellular localization
Cell membrane ; Single-pass membrane protein .
Tissue expression
Fetal brain,Fetal lung,Placenta,
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