Molecular weight (DA)
62kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CLCC1. AA range:391-440
Specificity
CLCC1 Polyclonal Antibody detects endogenous levels of CLCC1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
Function
function:Seems to act as a chloride ion channel.,similarity:Belongs to the chloride channel MCLC family.,
Protein name
Chloride channel CLIC-like protein 1
Other name
CLCC1; KIAA0761; MCLC; Chloride channel CLIC-like protein 1; Mid-1-related chloride channel protein 1
Human protein sequence Database
Q96S66
Mouse protein sequence database
Q99LI2
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Nucleus membrane ; Multi-pass membrane protein . Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes. .
Tissue expression
Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.
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